Amphetamine Salts XR
Generic: mixed amphetamine salts extended-release · Brand: Adderall XR® · Class: Stimulant — Schedule II (Amphetamine)
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How It Works
Adderall XR contains the same mixed amphetamine salts as Adderall IR but uses a beaded delivery system — half the beads release immediately and half release 4 hours later. This provides a smooth, all-day effect lasting approximately 10–12 hours from a single morning dose. The extended-release formulation eliminates the need for midday school or work doses, reduces rebound effects, and improves consistency of coverage compared to immediate-release.
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What It Treats
ADHD in Children 6+FDA-approved; once-daily dosing eliminates school nurse visits for midday doses
ADHD in AdultsFDA-approved; convenient once-daily coverage for work and daily activities
Consistent CoverageSmoother blood level curve reduces rebound mood crashes compared to IR formulations
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Dosing Overview
| Population | Start | Typical Range | Max |
|---|---|---|---|
| Children 6+ ADHD | 5–10 mg every morning | 10–30 mg/day | 30 mg/day |
| Adolescents ADHD | 10 mg every morning | 10–40 mg/day | 40 mg/day |
| Adults ADHD | 10–20 mg every morning | 20–60 mg/day | 60 mg/day |
Take once daily in the morning. Capsules can be swallowed whole or opened and sprinkled on applesauce — do not chew the beads. Do not take after noon to avoid insomnia.
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Side Effects
Common
- Decreased appetite
- Insomnia
- Dry mouth
- Headache
- Increased heart rate
- Stomach upset
- Irritability
- Mild anxiety
Call us if you notice
- Chest pain or palpitations
- Severe anxiety or psychosis
- Significant blood pressure elevation
- Worsening tics
- Signs of serotonin syndrome
Once-daily dosing is a major advantage for school-age children and working adults. Capsules can be opened and sprinkled on applesauce if swallowing is difficult — but never crush or chew the beads. Appetite suppression peaks at midday — a substantial breakfast before the dose helps.
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Tips for Success
Take in the MorningTake stimulants early in the day to avoid insomnia at night.
With or After BreakfastFood reduces stomach upset and helps avoid appetite suppression affecting meals.
Watch SleepIf it affects sleep, talk to your provider about adjusting timing or dose.
Avoid AlcoholAlcohol can worsen ADHD symptoms and interact with medication.
Stay HydratedDrink plenty of water — stimulants can cause dry mouth and dehydration.
Track Your ResponseNote focus, mood, appetite, and sleep daily to share with your provider.
Can Open CapsuleSprinkle on applesauce if needed — but never crush or chew the beads inside.
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Important Safety Information
Controlled Substance — Schedule II: Stimulant ADHD medications have a high potential for abuse and dependence. Take only as prescribed. Do not share with others. Store securely.
Cardiovascular Risk: Stimulants raise heart rate and blood pressure. Tell your provider about any heart conditions, high blood pressure, or family history of heart problems. Seek emergency care for chest pain, shortness of breath, or fainting.
Psychiatric Effects: Stimulants can cause or worsen anxiety, irritability, agitation, or psychosis — especially at higher doses. Report any new or worsening psychiatric symptoms.
Growth in Children: Stimulants can slow height and weight gain in children. Your provider will monitor growth at each visit.
Do Not Use With MAOIs: Combining stimulants with MAOIs can cause a dangerous, potentially life-threatening reaction. Wait at least 14 days after stopping an MAOI.
Pregnancy: Discuss risks and benefits with your provider. Do not stop without consultation.
Questions? I am here.
Reach me between appointments if you have concerns about side effects, notice mood changes, or have questions about your medication.
360-389-3712
info@rootedmindspsychiatry.com